Endocrine Abstracts

Introduction: Parathormone (PTH) is one of the major regulator of the bone and mineral metabolism. Elevated PTH levels in patients with primary and secondary hyperparathyroidism is thought to have negative effects on the cardiovascular system. In our study, we aimed to investigate a possible relationship between plasma PTH levels and coronary atherosclerosis.Methods: Fourty-two men and 35 women, a total of 77 patients were included the study who admitted...

Introduction: Vitamin D deficiency has become a major public health problem. It’s known that the effects of vitamin D are made by its receptors. VDR gene polymorphisms in susceptibility to different diseases demonstrated in many studies. The polymorphisms of VDR are ApaI, TaqI, FokI, and BsmI. BsmI is the most extensively studied polymorphism. In our study, the aim is to show the frequency of VDR BsmI gene polymorphisms and to show the relationship between polymorphisms a...

Primary hyperparathyroidism is a condition related with cardiovascular mortality and morbidity. Aim of this study is to investigate whether there is a difference between healthy controls, hypercalcemic patients with surgical decision and normocalcemic primary hyperparathyroidism patients for parameters like metabolic cardiovascular risk factors, carotis intima media thickness and pulse wave velocity and if there is a difference at patients with surgical decision 6 months after...

Aims: Self-monitoring of blood glucose (SMBG) is a necessary component of diabetes management but many patients with diabetes do not follow their healthcare proffesionals’ recommendations for self-monitoring. The aims of this study were to determine the proportion of patients with diabetes who perform SMBG in general practice and to identify patient-reported obstacles for SMBG.Methods: The study included 372 patients with type 1 or type 2 diabetes m...

Background: Adrenal carcinoma is rare endocrine cancer. Survival time is short and primary treatment is surgery.Methods: Four patients with histopathologically diagnosed as adrenal carcinoma between 2007 and 2013 were evaluated retrospectively.Results: Two of the patients were female and others were male. Their ages were 39, 50, 55 and 61 respectively. All the patients were admitted to the hospital with abdominal pain. Tumor diamet...

Introduction: The most common cause of diabetes insipidus is idiopathic. However, it may be also seen after metastasis to hypothalamic–pituitary region.Case: Fifty year old female patient with breast cancer was referred to our clinic with complaints of polyuria and polydipsia. Two years ago, she had diagnosed and after surgery, she has taken three cycles of cyclophosphamide+adriamycin+5-flurourasil than three cycles dosetaxel and finally seventeen c...

Primary mediastinal ectopic goiters are very rare and comprise about 1% of all mediastinal tumors. Blood supply of primary mediastinal goiter comes from local intrathoracic vessels. Compressing symptoms, diagnostic uncertainty, and the risk of malignancy support surgical excision.Case report: The patient is a 40-year-old woman with a 6-month history of progressive dyspnea, chest and back pain. Chest X-ray showed the left superior mediastinal mass was com...

Background and aim: Differentiated thyroid cancers are the most common endocrine cancer types. They are more common in women, but the prognosis tends to be poorer with men. We aimed to evaluate male and female patients with differentiated thyroid cancer.Subjects and methods: This retrospective study was performed in last 5 yearly hospital records of our hospital. All data about the patients’ conditions were obtained from hospital information system ...

Diffuse sclerosing variant of papillary thyroid carcinoma is a rare variant. It is usually seen in children and young adults.The thyroid gland is diffusely involved. It is characterized by scattered microscopic tumor islands, diffuse fibrosis, calcification, abundant lymphocytic infiltration and psammom body when compared with conventional papillary thyroid carcinoma. Usually the lesion does not cause mass but rather a dominant nodule in one lobe is present in 50% of cases. Ly...

Introduction: Gardner syndrome (GS) have very different extraintestinal manifestations such as include osteomas and thyroid cancers. Thyroid carcinomas associated with familial adenomatozis polyposis coli (FAP), are typically bilateral and multifocal. Our case presenting that GS included Graves’ disease (GD) and aggressive varyant of PTC.Case report: A 43-year-old men admitted to our out patient clinic for thyrotoxicosis investigation. He was compla...